2011-12-01から1ヶ月間の記事一覧

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セミナー等

「Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress andneurodegeneration.」 脳梗塞、NADPHオキシダーゼ (NOX4)、VA2870 脳梗塞は世界新第2位であり、一つだけ治療法が存在するものの90％の患者には禁忌である。 また、1…

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セミナー等

「Perinatal antidepressant exposure alters cortical network function in rodents.」 抗うつ薬、セロトニン、シタロプラム、自閉症スペクトラム 自閉症スペクトラム障害（ASD） ・広汎性発達障害のうち、高機能自閉症症、アスペルガー症候群などが、自閉…

慢性的ストレスは血管を弱くする、ネクロトーシスは網膜虚血の神経障害に影響する。

セミナー等

「Stress worsens endothelial function and ischemic stroke via glucocorticoids.」 ストレス、脳卒中、eNOS、大動脈輪、ミフェプリストン、 慢性的なストレスは、心拍数を有意に上昇させ、内皮依存性血管弛緩を障害し、スーパーオキシドの産生を増大させ…

Effect of Ketorolac Add-On Treatment on Intra-Ocular Pressure in Glaucoma Patients Receiving Prostaglandin Analogues./Turan-Vural E, Torun-Acar B, Acar S./Ophthalmologica. 2011 Nov 22.

論文

AbstractBackground/Aims: While topical ocular hypotensive agents cause secretion of endogenous prostaglandin (PG), systemic and topical non-steroidal anti-inflammatory agents inhibit its production; thus, they may interfere with therapeuti…

Comparison of Human Ocular Distribution of Bimatoprost and Latanoprost./Ichhpujani P, Katz LJ, Hollo G, Shields CL, Shields JA, Marr B, Eagle R, Alvim H, Wizov SS, Acheampong A,Chen J, Wheeler LA./J Ocul Pharmacol Ther. 2011 Dec 2.

論文

Abstract Purpose: This study investigated the ocular distribution of bimatoprost, latanoprost, and their acid hydrolysis products in the aqueous humor, cornea, sclera, iris, and ciliary body of patients treated with a single topical dose o…

Effect of propolis on proliferation and apoptosis of periodontal ligament fibroblasts. / Gjertsen AW, Stothz KA, Neiva KG, Pileggi R. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6):843-8.

論文

The most critical factors affecting the prognosis of an avulsed tooth are extraoral dry time and storage media used before replantation. Studies have analyzed different storage media to determine the ideal solution to preserve periodontal …

アミドイド抗体(NABs-A)、フェンサイクリジン、新しい受容体の概念

セミナー等

アルツハイマー病患者では、アミロイドに対する自己抗体(NAbs-A)が減少している。NAbs-Aはアミロイドのオリゴマー(特にダイマー）に結合しやすく、凝集を抑制することで毒性を示すアミロイドを除去している。 現在は根本的な治療薬として、バピネオズマブや…

In Vitro Study of Antiadipogenic Profile of Latanoprost, Travoprost, Bimatoprost, and Tafluprost in Human Orbital Preadiopocytes./Choi HY, Lee JE, Lee JW, Park HJ, Lee JE, Jung JH./J Ocul Pharmacol Ther. 2011 Nov 22.

論文

Abstract Purpose: To investigate the effect of prostaglandin F2α (PGF2α), latanoprost, travoprost, bimatoprost, and tafluprost on human orbital preadipocyte differentiation and intracellular lipid storage, and to reveal the potential mecha…

Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins./Sippl C, Bosserhoff AK, Fischer D, Tamm ER./Exp Eye Res. 2011 Nov;93(5):669-80. Epub 2011 Aug 27.

論文

Optineurin is a Golgi complex-associated ubiquitous protein with high expression levels in retinal ganglion cells (RGCs). Mutations in optineurin have been observed in rare hereditary cases of primary open-angle glaucoma and in amyotrophic…

Propolis prevents the effects of chronic alcohol intake on ocular tissues./Emre S, Yilmaz Z, Oztürk F, Emre MH./Ophthalmic Res. 2009;42(3):147-51. Epub 2009 Jul 23.

論文

AIM:This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure. MATERIAL AND METHOD:Wistar albino rats were used in this study. Rats were divided into 4 groups, and each grou…