Ophthalmologica. 2011 Nov 22.

論文

AbstractBackground/Aims: While topical ocular hypotensive agents cause secretion of endogenous prostaglandin (PG), systemic and topical non-steroidal anti-inflammatory agents inhibit its production; thus, they may interfere with therapeuti…

2011-12-10

Comparison of Human Ocular Distribution of Bimatoprost and Latanoprost./Ichhpujani P, Katz LJ, Hollo G, Shields CL, Shields JA, Marr B, Eagle R, Alvim H, Wizov SS, Acheampong A,Chen J, Wheeler LA./J Ocul Pharmacol Ther. 2011 Dec 2.

論文

Abstract Purpose: This study investigated the ocular distribution of bimatoprost, latanoprost, and their acid hydrolysis products in the aqueous humor, cornea, sclera, iris, and ciliary body of patients treated with a single topical dose o…

2011-12-07

Effect of propolis on proliferation and apoptosis of periodontal ligament fibroblasts. / Gjertsen AW, Stothz KA, Neiva KG, Pileggi R. / Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6):843-8.

論文

The most critical factors affecting the prognosis of an avulsed tooth are extraoral dry time and storage media used before replantation. Studies have analyzed different storage media to determine the ideal solution to preserve periodontal …

2011-12-05

In Vitro Study of Antiadipogenic Profile of Latanoprost, Travoprost, Bimatoprost, and Tafluprost in Human Orbital Preadiopocytes./Choi HY, Lee JE, Lee JW, Park HJ, Lee JE, Jung JH./J Ocul Pharmacol Ther. 2011 Nov 22.

論文

Abstract Purpose: To investigate the effect of prostaglandin F2α (PGF2α), latanoprost, travoprost, bimatoprost, and tafluprost on human orbital preadipocyte differentiation and intracellular lipid storage, and to reveal the potential mecha…

2011-12-05

Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins./Sippl C, Bosserhoff AK, Fischer D, Tamm ER./Exp Eye Res. 2011 Nov;93(5):669-80. Epub 2011 Aug 27.

論文

Optineurin is a Golgi complex-associated ubiquitous protein with high expression levels in retinal ganglion cells (RGCs). Mutations in optineurin have been observed in rare hereditary cases of primary open-angle glaucoma and in amyotrophic…

2011-12-01

Propolis prevents the effects of chronic alcohol intake on ocular tissues./Emre S, Yilmaz Z, Oztürk F, Emre MH./Ophthalmic Res. 2009;42(3):147-51. Epub 2009 Jul 23.

論文

AIM:This study is designed to investigate the protective effects of propolis in ocular tissues against chronic alcohol exposure. MATERIAL AND METHOD:Wistar albino rats were used in this study. Rats were divided into 4 groups, and each grou…

2011-11-30

TNFAIP3 Maintains Intestinal Barrier Function and Supports Epithelial Cell Tight Junctions./Kolodziej LE, Lodolce JP, Chang JE, Schneider JR, Grimm WA, Bartulis SJ, Zhu X, Messer JS, Murphy SF, Reddy N, Turner JR, Boone DL./PLoS One. 2011;6(10):e26352. Ep

論文

Tight junctions between intestinal epithelial cells mediate the permeability of the intestinal barrier, and loss of intestinal barrier function mediated by TNF signaling is associated with the inflammatory pathophysiology observed in Crohn…

2011-11-29

The Cytotoxic Effects of Preserved and Preservative-Free Prostaglandin Analogs on Human Corneal and Conjunctival Epithelium In Vitro and the Distribution of Benzalkonium Chloride Homologs in Ocular Surface Tissues In Vivo./Pellinen P, Huhtala A, Tolonen A

論文

Purpose: To investigate the cytotoxicity of benzalkonium chloride (BAC)-containing ophthalmic solutions of prostaglandin analogs (latanoprost, travoprost, bimatoprost, and preservative-free (PF) tafluprost), BAC mixture (BACmix) and BAC ho…

2011-11-24

Expression of Novel Opsins and Intrinsic Light Responses in the Mammalian Retinal Ganglion Cell Line RGC-5. Presence of OPN5 in the Rat Retina./Nieto PS, Valdez DJ, Acosta-Rodríguez VA, Guido ME./PLoS One. 2011;6(10):e26417. Epub 2011 Oct 17.

論文

THE VERTEBRATE RETINA IS KNOWN TO CONTAIN THREE CLASSES OF PHOTORECEPTOR CELLS: cones and rods responsible for vision, and intrinsically photoresponsive retinal ganglion cells (RGCs) involved in diverse non-visual functions such as photic …

2011-11-21

A history of the surgical management of glaucoma./Razeghinejad MR, Spaeth GL./Optom Vis Sci. 2011 Jan

論文

Many new surgeries have been devised since 1856, when von Graefe discovered that iridectomy is an effective surgical method for acute glaucoma treatment. Two years later, De Wecker presented sclerotomy as a procedure for chronic glaucoma. …

2011-08-21

Ras/Raf/ERKシグナル経路はアポトーシスを誘導する

論文

ERK and cell death Mechanisms of ERK-induced cell /Cagnol S /FEBS Journal アポトーシスによるプログラムされた細胞死は細胞自律的なメカニズムである。そのメカニズムはカスパーゼの活性化に制御される経路や損傷のために死へ向かう核で、周囲の細胞に…

2011-07-27

【Ras/Raf/ERK経路について】

論文

ERK and cell death Mechanisms of ERK-induced cell /Cagnol S et al. /FEBS Journal ERK1/2 (p44/42 MAPKとして知られており、それぞれ正式にMAPK3とMAPK1と名付けられている) は、細胞外シグナル制御キナーゼ (ERK) の2つのアイソフォームで、マイトジェ…

2011-07-25

Travoprost 0.004%/Timolol 0.5% Fixed Combination in Patients Transitioning from Fixed or Unfixed Bimatoprost 0.03%/Timolol 0.5%

論文

Travoprost 0.004%/Timolol 0.5% Fixed Combination in Patients Transitioning from Fixed or Unfixed Bimatoprost 0.03%/Timolol 0.5% Maria-Luise Scherzer · Ivana Liehneova · Francisco Jose Muñoz Negrete · Dietmar Schnober Introduction: Patients…